Electrochemical studies of glutathione monolayer assembled on a polycrystalline gold electrode

The glutathione (GSH) monolayer and complex monolayer of GSH-metallic ion on polycrystalline gold electrode were studied by using K₃Fe(CN)₆ as the redox probe. As for the GSH monolayer, it was found that the metallic ions could open the ion-gate in the monolayer dramatically in the order La³⁺> Pb²⁺>>Ba²⁺>Ca²⁺ whereas Zn²⁺ ion closed the ion-gate. The complexes of GSH-metallic ions were capable of self-assembling the different kind of monolayer. All the differences were related to the structural configuration of the anchored GSH molecule, which changed with different metallic ions or pH. Biography:Fang Cheng (1971-) male, Ph. D, research direction: electroanlysis.     

中国科技园区域创新能力的智能评价

对中国科技园区域创新能力的评价体系进行了阐述。在现有评价指标体系的基础上，结合人工智能的最新研究成果，针对目前中国科技园区域创新能力评价方法存在的不足，提出了基于数据描述的智能评价方法，并将其应用到中国科技园区域创新能力的评价中，取得了较为理想的效果。     

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the generation of amyloid beta peptide (Abeta) in Alzheimer disease. We report here that inherited variants in the SORL1 neuronal sorting receptor are associated with late-onset Alzheimer disease. These variants, which occur in at least two different clusters of intronic sequences within the SORL1 gene (also known as LR11 or SORLA) may regulate tissue-specific expression of SORL1. We also show that SORL1 directs trafficking of APP into recycling pathways and that when SORL1 is underexpressed, APP is sorted into Abeta-generating compartments. These data suggest that inherited or acquired changes in SORL1 expression or function are mechanistically involved in causing Alzheimer disease.     

试论中国教师的"中国特色"

中国教师在当今这个时代,既不能离开民族的"土壤",也不可能离开国际的"气候",因此,当代中国教师的"中国特色"应包括三大要素:第一是足够的民族自信心和深厚的中华文化底蕴;第二是注重为人师表的风范和讲究人格形象;第三是与时俱进的精神和世界一流的专业化水平。     

关于W变换性质的进一步讨论

根据W变换和Delta函数的定义，讨论了函数f(x)的线性函数af(x) b的W变换和函数Ⅱi-1^n，(x)的W变换问题，并推广了W变换的线性性质，得到了几个进一步的结果．     

“情报门”还是“情报丑闻”?

近日报刊、电视等媒体上常出现"情报门"、"凯利门"等词.前者指伊拉克武器情报事件,后者指武器专家凯利自杀事件.     

氢键分子系统的二分量孤子偶模型中的非谐特性

以氢键分子系统中二分量孤子模型为基础，采用直接微扰方法，研究了氢键系统中非谐相互作用下扭结孤子偶的运动特性，获得了3次方到4闪方非谐项古孤子偶的非对称解，计算了源于非谐项下孤子偶的能量，与实验观察相一致。     

基于神经网络的企业信用等级评估

企业信用等级评估是金融领域重要的问题，论文采用人工神经网络模型研究企业信用等级的评估问题，按照企业样本在信用等级的分布状况来抽样，然后，根据企业样本性质的不同，将其分为制造业和非制造业两大类，利用偏相关分析方法建立了企业信用评级的指标体系，此外，还介绍了几种企业信用评级常用的评估模型，并将神经网络评估模型的性能和其他的信用评估模型作了比较，实验结果表明神经网络模型具有更好的预测准确性。     

面向对象的系统活动描述方法

通过实例介绍了系统活动作为一个对象／类的概念，给出了对系统活动进行分析和建模的一般步骤，提出了系统活动描述的形式化方法。     

轴拉杆随机分析的域外奇点法

采用随机域外奇点法对轴拉杆件进行了分析．考虑杨氏模量的不确定性，得到了不同相关类型、不同相关长度下的解析解，并分析了相关类型、相关长度以及随机场中点离散法对位移方差的影响．